Eden Fox, an artist on the brink of her big break, sets off for a run before her first exhibition. When she returns to the home she recently moved into, Spyglass, an enchanting old house in Hope Falls, nothing is as it should be. Her key doesn’t fit. A woman, eerily similar to her, answers the door. And her husband insists that the stranger is his wife.

Bryden and Sam have it all: thriving careers, a smart apartment in a luxury condominium, supportive friends and a cherished daughter. The perfect life for the perfect couple. Then Sam receives a call at his office. Bryden–working from home that day–has failed to collect their daughter from daycare. Arriving home with their little girl, he finds his wife’s car in the underground garage. Upstairs in their apartment her laptop is open on the table, her cell phone nearby, her keys in their usual place in the hall. Except Bryden is nowhere to be seen. It’s as if she just walked out.

Ashley Bowers is shocked by the sudden death of her sister, whom she hasn't seen or heard from in years. Grieving for the bond they once shared and wallowing in the knowledge that any chance of reconciliation is gone forever is one thing. Welcoming her sister's thirteen-year-old daughter—a girl Ashley has never even met—into the home she shares with her husband and two children is another.

St. Medard’s Bay, Alabama is famous for three things: the deadly hurricanes that regularly sweep into town, the Rosalie Inn, a century-old hotel that’s survived every one of those storms, and Lo Bailey, the local girl infamously accused of the murder of her lover, political scion Landon Fitzroy, during Hurricane Marie in 1984.

Lottie Jones thought her crimes were behind her. Decades earlier, she changed her identity and tucked herself away in a small town. Her most exciting nights are the weekly bingo games at the local church and gossiping with her friends. When investigative journalist Plum Dixon shows up on her doorstep asking questions about Lottie’s past and specifically her involvement with numerous unsolved cases, well, Lottie just can’t have that. But getting away with murder is hard enough when you’re young.

When Julie Buckley, a successful mystery writer, suspects her husband of cheating, she turns to her best friend, Darby, for advice. When Darby suggests couples therapy, Julie and Oliver find themselves discussing Oliver’s betrayal with their new therapist, Liza. Liza is competent and reassuring, and her advice and Oliver’s openness to change seem to be helping the couple rebuild their relationship.

It was the Crime of the Decade. Pathological sibling rivalry. Bitter, all-consuming envy. Whatever the cause—and everyone has an opinion—it led Georgia Cartwright who was adopted as a newborn, to kill the younger, biological daughter of her wealthy, socially prominent family. Georgia is being kept at an institution where the most violent offenders are held while she waits to see if she is ruled not guilty by reason of insanity.

In 1942, six people destroyed Anna Matheson’s family. Twelve years later, she’s ready for retribution. Under false pretenses, Anna has lured those responsible for her family’s downfall onto a luxury train from Philadelphia to Chicago, an overnight journey of thirteen hours. Her goal? Confront the people who’ve wronged her, get them to confess their crimes, and deliver them into the hands of authorities waiting at the end of the line. Justice will at last be served. But Anna’s plan is quickly derailed by the murder of one of the passengers.

Growing up in an isolated cabin in Montana in the mid-1990s, Jane knows only the world that she and her father live in: the woodstove that heats their home, the vegetable garden where they try to eke out a subsistence, the books of nineteenth-century philosophy that her father gives her to read in lieu of going to school. Her father is elusive about their pasts, giving Jane little beyond the facts that they once lived in the Bay Area and that her mother died in a car accident, the crash propelling him to move Jane off the grid to raise her in a Waldenesque utopia.

Beckett Bowery never thought she’d return to Wyatt Valley, a picturesque college town in the Virginia mountains steeped in tradition. Her roots there were strong: Beckett’s parents taught at the college, and she never even imagined studying anywhere else—until a tragedy her senior year ended with two local men dead, and her roommate on the run, never to be seen again…

Twenty-two years ago, Claire Campbell’s older sister, Natalie, disappeared shortly after her eighteenth birthday. Days later, her blood was found in a car, a man was arrested, and the case was swiftly closed. In the decades since, Claire has attempted to forget her traumatic past by moving to the city and climbing the ranks as an investigative journalist... until an unexpected call from her father forces her to come back home and face it all anew.

It’s been ten years since Jade lost her father in a tragic accident, and the lingering guilt and grief have dragged her down to rock bottom. Then one night, she’s out at a restaurant and sees the impossible through the window: her father, alive. By the time she reaches the crowded sidewalk, he has disappeared. After so much despair, Jade isn’t going to lose him again—no matter what sinister truths may come from following him.

Strange things happen in Fell, New York. A mysterious drowning at the town’s roadside motel. The unexplained death of a young girl whose body is left by the railroad tracks. For the Esmie siblings—Violet, Vail, and Dodie—the final straw was the shocking disappearance of their little brother. It started as a normal game of hide-and-seek. The three closed their eyes and counted to ten while Ben went to hide. But this time, they never found their brother—he was gone and the ongoing search efforts turned up no clues.

When seventeen-year-old Isla Richardson is killed in a hit-and-run incident, a community’s lives are thrown into disarray. For Isla’s mum, Abby, it is her second devastating bereavement, having lost her husband five years ago. As Abby begins to uncover secrets about Isla’s life, she’s forced to rethink everything she thought she knew about her family.

In My Sister's Daughter, Ashley Bowers hopes her recently orphaned thirteen-year-old niece, Serena, will blend seamlessly into her own family once they've all had time to mourn. But as days become weeks, a series of troubling occurrences turn the once-peaceful Bowers home into a maelstrom of accusation, denial, and fear. Is Serena simply acting out after the tragic loss of both her parents? Or is something far more dangerous happening under Ashley's own roof?

In My Sister's Daughter, Ashley Bowers hopes her recently orphaned thirteen-year-old niece, Serena, will blend seamlessly into her own family once they've all had time to mourn. But as days become weeks, a series of troubling occurrences turn the once-peaceful Bowers home into a maelstrom of accusation, denial, and fear. Is Serena simply acting out after the tragic loss of both her parents? Or is something far more dangerous happening under Ashley's own roof?

At age thirty-eight, Jonathan Gluck, a new father with a promising journalism career, was shocked to learn he had multiple myeloma, a rare, incurable blood cancer. He was told he had eighteen months to live. That was more than twenty years ago. Gluck isn’t just something of a medical miracle. He’s also part of a growing population. Thanks to revolutionary medical advances, many cancers and other serious illnesses are no longer death sentences but chronic diseases people can often live with for years.

A year after the tragic death of her four-year-old son, Charlotte Fleming is sleepwalking through life, trapped in a spiral of devastating grief. Then, she sees something online that jolts her awake: her son, Sebastion, alive and well . . . in a stranger's social media post. Charlotte desperately wants to believe that what she sees is real, that her son is out there somewhere waiting to be brought home. After all, Sebastion's body was never recovered from the accident that supposedly killed him.

Lily—a bored, beautiful twenty-something—wakes up on a remote desert compound, alongside nineteen other contestants competing on a massively popular reality show. To win, she must outlast her housemates to stay in the Compound the longest, while competing in challenges for luxury rewards like champagne and lipstick, plus communal necessities to outfit their new home, like food, appliances, and a front door. Cameras are catching all her angles, good and bad, but Lily has no desire to leave: why would she, when the world outside is falling apart?

Ever since she was a teenager, Tessa Nilsson has been consumed by the story of four friends who disappeared. As her true crime fervor turned into a wildly popular podcast, Tessa covered Sweden’s most gruesome cases, but could never find the answers behind what happened to these women who disappeared. Now Tessa’s podcast has crashed and burned, any chance she had at uncovering the truth vanishing with it.

For fifteen years, Joanna Sokol filled private notebooks with her confusion, humor, and anger about the strange world of American street medicine. As her career progressed, she found herself taking notes on scraps of paper, backs of gloves, and margins of EKG printouts. She read about the history that brought ambulances into their current role as the caretakers of society’s forgotten, and spoke to her colleagues about their own experiences and perspectives. Those reflections are collected here, in a series of raw, powerful essays about the state of American medicine.

Ashley Bowers is shocked by the sudden death of her sister, whom she hasn't seen or heard from in years. Grieving for the bond they once shared and wallowing in the knowledge that any chance of reconciliation is gone forever is one thing. Welcoming her sister's thirteen-year-old daughter—a girl Ashley has never even met—into the home she shares with her husband and two children is another.

Twenty-two years ago, Claire Campbell’s older sister, Natalie, disappeared shortly after her eighteenth birthday. Days later, her blood was found in a car, a man was arrested, and the case was swiftly closed. In the decades since, Claire has attempted to forget her traumatic past by moving to the city and climbing the ranks as an investigative journalist... until an unexpected call from her father forces her to come back home and face it all anew.

Courtney Gray's tranquil family vacation is shattered when she hears a blood-curdling scream from the lakeside cottage next door. There she finds the lifeless bodies of her brother and sister-in-law. Her teenage niece Reese is nowhere to be found, while her nephew Wyatt lies asleep upstairs, unharmed.

Growing up in an isolated cabin in Montana in the mid-1990s, Jane knows only the world that she and her father live in: the woodstove that heats their home, the vegetable garden where they try to eke out a subsistence, the books of nineteenth-century philosophy that her father gives her to read in lieu of going to school. Her father is elusive about their pasts, giving Jane little beyond the facts that they once lived in the Bay Area and that her mother died in a car accident, the crash propelling him to move Jane off the grid to raise her in a Waldenesque utopia.

Thom and Wendy Graves have been married for over twenty-five years. They live in a beautiful Victorian on the north shore of Massachusetts. Wendy is a published poet and Thom teaches English literature at a nearby university. Their son, Jason, is all grown up. All is well…except that Wendy wants to murder her husband.

In 1942, six people destroyed Anna Matheson’s family. Twelve years later, she’s ready for retribution. Under false pretenses, Anna has lured those responsible for her family’s downfall onto a luxury train from Philadelphia to Chicago, an overnight journey of thirteen hours. Her goal? Confront the people who’ve wronged her, get them to confess their crimes, and deliver them into the hands of authorities waiting at the end of the line. Justice will at last be served. But Anna’s plan is quickly derailed by the murder of one of the passengers.

When Audrey Collet’s ex Tyson calls, threatening to expose the skeletons in her closet unless she helps him figure out who is blackmailing him, she wants nothing more than to refuse. Though their relationship ended over a decade ago, the scars are deep. And since his tech company made him a billionaire, he’s become more than a little eccentric . . . and paranoid. But a foot has washed ashore in the Everglades—that’s right, an actual human foot, encased in an Air Jordan—and Tyson is quick to remind Audrey that it’s one whose long-dead owner they both have a connection to.

All I want is to be innocent again. But that's not how it works. Especially not after the Wheel. The three Bishop sisters grew up in privilege in the moneyed suburbs of Detroit. But as the auto industry declined, so did their fortunes. Harper, the youngest, is barely making ends meet when her beloved, charismatic sister Pam—currently in the middle of a contentious battle with her ex-husband—and her eldest sister, Debra, approach her about joining an exciting new club.

For twenty-four-year-old Jane, finding love in New York City is even harder than making it as a playwright. So when Jane meets Colin, she can’t believe her luck: they’re perfect for each other. Even when Colin breaks off their relationship after six dates, Jane knows this is just a stumbling block. She’ll get him back. She knows she will. That is, until Colin starts dating Zoe—perfect, luminous Zoe. Even worse, she’s actually kind of nice. But Zoe doesn’t have what it takes to love Colin. All Jane has to do is prove it, and they’ll be so happy together.